when does castiel first appear in supernatural

Hugh sacrificed his chance at the National Medical Research Council to save his wife Quinn, who had late-stage liver cancer. He sold family heirlooms to fund her treatment, but Quinn used the money to buy a car for her first love, James. She became obsessed with their past together, ignoring her son Luke's feelings. Hugh and Luke gave her three chances to change, but she refused. Finally, Hugh joined the National Physician Program and left with Luke. After he departed, Quinn regretted her actions, but it was too late to make amends.

As a child, Jensen Fort hates studying until his mother hires Carine Nett as his little caretaker. Seeing Carine's many virtues, Jensen becomes disciplined and studious,secretly vowing to marry her when he grows. Now a global business tycoon and the world's richest man, Jensen's first act after achieving success is returning to the countryside to marry Carine.

Modern-day gamer Leo Kane dies suddenly after an all-night gaming session and wakes up in another world as Grecan's most feared assassin, Cipher. Upon awakening, he's hired by Imperial Guard officer Hugo Spence to kill a woman named Lady Brooks. Intending to take the money and slack off, Leo's plan collapses when he's captured by his target, Poppy Brooks, who discovers his assassination mission. After Leo bravely drives off a group of bandits, Poppy's view of him changes. When she later learns that Leo once saved her life, their relationship begins to thaw, sparking a bond neither expected in a world built on blades and secrets...

In the Yolham Kingdom, Empress Christine Shaw gains weight after childbirth and is cast aside by the emperor and even her own son, who has been manipulated by the cunning Noble Consort Rosalie Cooper. Humiliated and killed, Christine's body is taken over by a modern doctor determined to seek justice. Using modern technology and medical skills, she slims down, stuns the court with her beauty and talent, and rises as a respected empress. The emperor gradually falls for her and tries to win her back,but Christine wants nothing to do with him. In the end, she chooses freedom and sets off to explore the world with the grand emperor.

Adam Irwin, the factory's only college graduate, secretly loved the director's daughter, Rhea Catton. Risking his life to save her at the annual party, he was falsely accused of rape, ruining his life. Reborn that day, Adam exposes the truth, outsmarts Rhea and Jeff Payne,finds justice and true love, while her family regrets trusting the wrong man.

Out of desperation, Queenie Xavier sells her first night to Yarden Lewis, the man she's secretly loved for eight years. Yarden enjoys the thrill but keeps her as a secret lover, never imagining it could last. She feels the same. When the time comes, she walks away.Only then does Yarden realize he's been in love with her to the very core all along.

While delivering food, Sara Scott accidentally collided with Toby Luke, the son of the richest man in the city. Desperate to raise money for her boyfriend's research fees,Sara,feeling guilty, sold her electric bike, worth over a thousand dollars, to Toby for five thousand. This led Toby to mistakenly think she was a gold-digger. The two, who had no prior connection, became entangled due to Toby's father's will, which stipulated that he must marry the daughter of his first love to inherit the vast fortune, and that daughter turned out to be Sara. In order to secure the inheritance, Toby schemed to separate Sara from her scum boyfriend and tried to make her fall in love with him. However, in the process of his carefully laid plans, he found himself falling for Sara first.

Mia's world turned upside down when her first love, Logan Henry, re-entered her life with his young daughter, Jade Henry. As Jade became a constant presence in the family, Mia's relationship with her own daughter, Molly Justin, grew increasingly strained. Feeling overshadowed and repeatedly pushed aside, Molly slowly closed off her heart until one day, she left with her father, Mason Justin. Only after their departure did Mia awaken to the pain she'd caused. The weight of her indifference and the void left by her daughter's love began to consume her, plunging her into a spiral of irreparable remorse.

Adopted by werewolf hunters, 18-year-old Staysha's mission to kill her first werewolf changes when she unknowingly spends a night with the charming Alpha King, igniting a forbidden romance.

At his brother's engagement banquet, elite tycoon Larry Nell stunned society by marrying an outsider, Coral Baker, a whirlwind union fueled by rumors of a scandalous public kiss. In truth, she was just a paid stand-in, hired to play the dutiful ""Mrs. Nell"" amid his mercurial whims.What began as a transaction, his need for a decoy, her need for cash, slowly defied the contract. Amendments piled up, each edit eroding the cold terms with unspoken desire.By the end, no one remembered the pretense. Only the love story remained.

Nova was separated from her mother as a child and has been searching for years. Now a wealthy tycoon, she returns home, where her bullied mother suffers. Will her arrival transform her mother’s fate?

In the previous life, Jonathan Shane gave his all for his family. However, he was framed by his adopted brother Jacob, put in jail, abandoned by his family, and died with regrets in the end. This time, he refused to take the blame for Jacob and revealed the truth of the hit-and-run, but his mom and sisters still took Jacob's side. So, Jonathan chose to cut ties with his family and decided to take back what had been stolen from him.

Born into a rural family that favored sons, Diane Quinlan fell in love at 18 with educated youth Ethan Lister and followed him to the city with their daughter. His family despised her background and made her life miserable, even falsely accusing her daughter of theft. Finally breaking free with her daughter, Diane meets Nelson Zeller, a disabled veteran. When the Lister family continues harassing them, Nelson steps up to protect them both. With his support, Diane educates herself, leverages her tailoring talents, and establishes a clothing factory. Under her devoted care, Nelson’s legs gradually recover. From abandoned wife to independent factory owner, Diane rewrites her destiny, finding love and partnership with Nelson along the way.

Faye discovers that her fiancé is having an affair with the wife of secret billionaire Arvin Sterling, so she takes revenge on him by getting intimate with Arvin. However, it turns out to be Arvin’s scheme to lure Faye in his seduction game......

April Simpson takes the blame for murder to protect Reuben Rogers.Seven years later, now facing execution, she's granted ten days of compassionate leave to earn money for her mother's surgery by working as a hostess. There she encounters Reuben, who has become a business mogul. Believing she abandoned him for money years ago, he humiliates her with his wealth. On execution day, Dexter Edwards arrives with new evidence that saves her life.After her release, April desperately needs a liver transplant due to complications from her previous donation. But Reuben forcibly takes the donor liver for Kiara Simpson instead, causing April's mother to die suddenly. In despair, April attempts suicide. Finally learning the truth, a maddened Reuben searches frantically until he finds April, but she now suffers from amnesia. He carefully guards this final tenderness between them, but the truth will eventually shatter this fragile peace.

Queenie was taken out of the orphanage by her parents. She thought she could finally live a happy life, but upon returning home, she discovered the existence of a favored fake daughter, Winnie. Fearing that Queenie would take everything from her, Winnie resorted to all sorts of underhanded tactics. To frame Queenie, she even pushed her fiancé's sister down the stairs, leaving her in a vegetative state. In court, Queenie's parents biasedly supported Winnie and deleted surveillance footage. Her brother even testified against her, sending her to prison. After five years of suffering, Queenie emerged from prison feeling hopeless and no longer yearning for familial bonds. She just wanted to escape that home.\

Erin Sanders finds herself entangled in a risky romance with her billionaire arch-rival, Nolan Duffy, who covertly becomes her house boy. But when his deceptions are exposed, threatening her heart and her company, Erin must choose between safeguarding her family legacy or embracing their unconventional love..

With her family facing bankruptcy, her father tragically ending his own life, and her mother suffering from severe illness, Amy Cole finds herself with no option but to accept money from Will Ford's mother and leave Will. Several years later, Will's mother looks for her again, asking her to return to Will's side. It turns out that after Amy breaks up with him, Will has been fooling around outside and has no direction in his life. He keeps changing his girlfriends every now and then. On top of that, he even wants to marry a scandalous celebrity. Hearing that, Amy knows that her chance has come. What's wrong with pursuing the man she loves all over again? However, unbeknownst to her, all of this is part of Will's trap.