when did patrick dempsey leave grey's anatomy

Simon was the son of Fletcher and Yvette, but his birth resulted from Fletcher's drunken one-night stand. From the moment Simon was born, Fletcher treated him coldly and showed clear favoritism toward his first love's son, Richard. This ongoing discrimination caused great pain for both Simon and Yvette, which eventually led Yvette to leave with Simon. After leaving, Yvette met Simon's cello teacher,Matthew,who gave Simon a fatherly love he had never known before.The three of them supported each other closely.Meanwhile,Fletcher, having realized his past mistakes, could only silently watch as Simon thrived under Matthew's care, bearing alone the pain caused by his own wrongdoings.

After losing her parents, Anna was taken in by Mrs. Kane—her mother’s closest friend—and grew up alongside the Kane brothers, Gordy and Jonathan. The two boys were stars of their school's hockey club, while Anna became their manager, always cleaning up their messes and keeping everything running smoothly. For years, the three were inseparable, perfectly in sync both on and off the ice. But everything changed when Katie, the school beauty, set her sights on Anna’s position. Through carefully plotted schemes and whispered lies, she framed Anna for mistakes, drove a wedge between her and the brothers, and slowly turned them against her. Humiliated and heartbroken, Anna grew distant from Gordy and Jonathan. Eventually, she gave up and transferred to another school, where she met hockey star Ethan and became his manager instead. Only after she was gone did the Kane brothers begin to see the truth about Katie—and by then, it was far too late.

Harrison Chambers signed a gratitude contract with Kira Sue's mother, giving up his dream of developing of northwest to marry into the Sue family. For five years, he took care of Kira with great devotion. However, after a tragic fire, Harrison realizes that his efforts could not win her heart. She still harbors feelings for her first love, Zane Lee, who is about to return from abroad. Deciding to leave, Harrison heads to the northwest. Only after his departure does Kira realize her true feelings, but it is already too late.

Mark Dalton engaged in charity work and financially supported Carla Fulton, who was in poverty. Carla mistakenly believed that she held a special place in Mark's heart and gradually became arrogant. Five years later, after graduating from university, Carla, in an attempt to show off, lied that Mark was her brother and brought her classmates to intern at his company. Mark, busy with the company's IPO, delegated the task of arranging the internships to his subordinates. The subordinates did not dare to stop her, allowing her to act recklessly within the company. She fired the technical team and declared herself the chairperson. When Mark was negotiating a partnership with Saturn Group, Carla's outrageous behavior caused the deal to fall through, and Mark was so furious that he fainted and was hospitalized. Carla continued her reckless actions, pushing the company to the brink of bankruptcy, and even planned to sell it. After Mark regained consciousness, he exposed her lies. Resentful, Carla teamed up with a rival company to sabotage Mark's projects. In the end, Mark uncovered the conspiracy, Carla was arrested, and the company successfully went public with the support of Saturn Group.

Sierra Lowe, a genius from the future research institute, dies unexpectedly and wakes up 100 years in the past as the fiancée of Commander Ethan Nacht. Her plan is simple: lay low, earn money, and avoid trouble. And when the ninth wife finally rises to power, she’ll happily step aside. But on their wedding day, Commander Ethan hears her inner thoughts loud and clear: “So this is Ethan Nacht, the guy who secretly slept with the ninth wife?”Ethan was baffled: "Father only had eight wives. Where did the ninth come from?"

William Coffey and Shelly Richards had been together for years, deeply in love. But just before they could get married, tragedy struck—William's sister Lea died in an incident involving Shelly's younger brother. The Coffey family was devastated and blamed Shelly, their grief turning into resentment. While William was in the hospital, his mother forced Shelly to leave. At the time, Shelly was already pregnant, but with nowhere to turn, she had no choice but to leave the country. Five years later, Shelly returned and ran into William again. The feelings he had buried for so long came rushing back. He still resented her for disappearing without a word, but no matter how hard he tried, he couldn't stop loving her.

Six years ago, singer Emma Hadley developed a kidney disease after childbirth, was abandoned by her boyfriend Tyler, and was told that her daughter had died. In reality, Tyler saved her by donating his kidney, but because he borrowed money for the surgery from Michael, a popular singer who had a crush on Emma, he was forced to leave with their daughter. Six years later,Emma became a renowned superstar in the music industry, still haunted by thoughts of her daughter. Her daughter Lily, singing on the street to raise money for her father Tyler's surgery,accidentally encountered Emma...

As the most powerful man in Rivton City, Barlow Sapir hated the most when women threw themselves at him. However, the first time he met Elvira Ann, the latter solemnly declared, "I'm not interested in you, Barlow Sapir." The second time, she swore to God, "I won't sleep with you." Then there was the third time… the fourth time… But little did Elvira know, Barlow Sapir desired nothing more than her love. The more she tried to get rid of him, the more he yearned for her. What could she do?

After her fiancé and stepsister betrayed her, Zoey Quin hastily married Henry Tyler, her fiancé's uncle. She thought it was just a mutually beneficial cooperation, but little did she know that Henry had loved her for years. After several twists and turns, Zoey was touched by Henry's tenderness and attention to detail, and she finally learned of his long-hidden affection. Then they lived happily ever after.

In a desperate attempt to fulfill his comatose grandmother's greatest wish, Claude impulsively brought over a pregnant woman at the hospital and told his grandmother that the woman was carrying his child. Miraculously, his grandmother pulled through. However, that very night, Claude dreamed about the pregnant woman... Chloe initially thought running into her baby's biological father at the hospital was a mere coincidence—but little did she know, this man would keep reappearing in her life from that day on...

Ten years ago, the once optimistic Sam Rider was forced to leave his family and venture to a distant land due to a misunderstanding. He lived alone, experiencing life's trials and tribulations. During this time, Sam encountered a life-threatening accident, hanging by a thread until he was saved by a girl, Helen Foster. Grateful for her rescue, he silently stays by her side and protects her to repay the debt of saving his life. The two eventually become lovers. However, life after marriage isn't a happy one. The burdens of life and various misunderstandings place immense pressure on both of them, dealing a huge blow to their relationship. Nevertheless, Sam doesn't give up. In the end, through his efforts, Sam earns approval from Helen's family and ultimately lives a happy life with Helen.

April Simpson takes the blame for murder to protect Reuben Rogers.Seven years later, now facing execution, she's granted ten days of compassionate leave to earn money for her mother's surgery by working as a hostess. There she encounters Reuben, who has become a business mogul. Believing she abandoned him for money years ago, he humiliates her with his wealth. On execution day, Dexter Edwards arrives with new evidence that saves her life.After her release, April desperately needs a liver transplant due to complications from her previous donation. But Reuben forcibly takes the donor liver for Kiara Simpson instead, causing April's mother to die suddenly. In despair, April attempts suicide. Finally learning the truth, a maddened Reuben searches frantically until he finds April, but she now suffers from amnesia. He carefully guards this final tenderness between them, but the truth will eventually shatter this fragile peace.

April Simpson takes the blame for murder to protect Reuben Rogers.Seven years later, now facing execution, she's granted ten days of compassionate leave to earn money for her mother's surgery by working as a hostess. There she encounters Reuben, who has become a business mogul. Believing she abandoned him for money years ago, he humiliates her with his wealth. On execution day, Dexter Edwards arrives with new evidence that saves her life.After her release, April desperately needs a liver transplant due to complications from her previous donation. But Reuben forcibly takes the donor liver for Kiara Simpson instead, causing April's mother to die suddenly. In despair, April attempts suicide. Finally learning the truth, a maddened Reuben searches frantically until he finds April, but she now suffers from amnesia. He carefully guards this final tenderness between them, but the truth will eventually shatter this fragile peace.

Keith's daughter had a lifelong strawberry allergy. After eating a cookie with hidden strawberry ingredients, she died from an allergic reaction.Keith,already battling cancer, found out his wife Hollie was the one who gave her the cookie. To spare her the guilt, he took the blame. But Hollie,believing he killed their daughter, resented him deeply and made him suffer. Only as Keith lay dying did she learn the truth—too late to make things right.

Olivia Turner loved Zacharias Larson for nine years, but in the tenth year, she found herself imprisoned by Zacharias's own hands. Falsely accused of her grandfather's death and giving birth to another man's child, Olivia faced a wrongful sentence. The true culprit behind the conspiracy was her sister, mistakenly raised by the Turner family and later recognized into the affluent Larson family. Deception, identity substitution, and framing orchestrated Olivia's downfall. It wasn't until the brink of death that Olivia discovered the truth. Yet, Zacharias, the one person she needed to believe her, remained skeptical. Only upon witnessing her lifeless body did he descend into madness.

Olivia Turner loved Zacharias Larson for nine years, but in the tenth year, she found herself imprisoned by Zacharias's own hands. Falsely accused of her grandfather's death and giving birth to another man's child, Olivia faced a wrongful sentence. The true culprit behind the conspiracy was her sister, mistakenly raised by the Turner family and later recognized into the affluent Larson family. Deception, identity substitution, and framing orchestrated Olivia's downfall. It wasn't until the brink of death that Olivia discovered the truth. Yet, Zacharias, the one person she needed to believe her, remained skeptical. Only upon witnessing her lifeless body did he descend into madness.

Sara and Nyla were sisters of the Caldwell family. In their previous life, Sara married Eddie, a penniless man, but his family unexpectedly struck it rich and lived in prosperity. Meanwhile, Nyla married Tyler, a powerful military officer, but he died shortly after their wedding, driving her into madness. Blinded by jealousy over Sara's happiness, Nyla stabbed her to death—only to be killed by Sara's dying strike.When the sisters were reborn, returning to the moment of the marriage proposals, Nyla decided to snatch Eddie away. Little did she know that Sara had also been reborn and would later prevent Tyler's death, ending up far more successful than Nyla this time…

After Zack Johnson went abroad, Cindy Thomas married Calvin Steven and had a daughter Angela. One day, Zack came back with his daughter Felice. Cindy cared so much about them and let Felice call her Mom. On the other side, she had been treating Calvin and Angela like strangers. After feeling disheartened on her birthday, Angela decided to leave with Calvin and start a new life.